Osteosarcopenic obesity (OSO) has been associated with immobility, falls, fractures, and other dysfunctions, which could increase mortality risk. However, its etiology remains unknown. Recent studies revealed that sedentarism, fat gain, and epigenetic regulators are critical in its development. One effective intervention to prevent and treat OSO is exercise. Therefore, in...
High fructose intake through sugar-sweetened beverages induces metabolic and endocrine changes in adipose tissue (AT). It has been suggested that microRNAs (miRNAs) contained in extracellular vesicles (EVs) are some of the endocrine signals secreted by adipocytes, which can regulate diverse cellular processes, including adipocyte differentiation and metabolism. However, the effect...
Obesity is a growing public health problem globally and nationally. Currently the World Health Organization (WHO) has pointed to obesity as the epidemic of the century. This problem has been classified as a disease that causes accumulation of energy in the form of triglycerides (TG) in body adipose tissue (AT)....
Eicosapentaenoic acids (EPA) and docosahexaenoic (DHA) are omega-3 polyunsaturated fatty acids With the beneficial effects on preventing various diseases in which the inflammation plays a fundamental role. Since these omega - 3 fatty acids are ligands for PPARs, they could have an impact on metabolic activity. Therefore, they could exert...
El carcinoma hepatocelular (HCC) constituye la cuarta causa de muerte relacionada con cáncer a nivel mundial y la tasa de incidencia de este continúa en ascenso, tanto en hombres como en mujeres. La principal causa ha sido el consumo de dietas hipercalóricas ricas en carbohidratos como la fructosa. La dieta...
Uno de los principales problemas de salud en México es la diabetes mellitus tipo 2 (DT2). La obesidad o el sobrepeso son factores de riesgo para desarrollar DT2. Existe una relación muy importante entre estas patologías ya que se caracterizan por generar un estado de inflamación crónica que se manifiesta...
Obesity is one of the most common diseases in the general population. It is not only a social and cosmetic problem but also a serious ailment that leads to several genetic, metabolic and psychological disturbances. Its prevalence is rapidly increasing and although the rate of population affected is variable in...
The overweight and the obesity are defined as abnormal or excessive fat accumulation that may impair the health. According to the World Health Organization, in 2005 approximately 1.6 billion of adults had overweight, whereas 400 million of adults were obese. Overweight and obesity are considered risk factors for developing type...
Metabolic diseases are those which affect the metabolism in a direct manner. Both obesity and hypertension are a major concern in public health due to its high prevalence in Mexico, said prevalence being calculated to be a 34.6% which suffer from obesity and 44.9% hypertension. The etiology of both diseases...
Resultados. Los niveles plasmáticos de LCN2 en los grupos de estudio fueron: 70.81 ng/mL (C); 65.8 ng/mL (Pd) y 42.36 ng/mL (Db); asimismo, se observaron diferencias de dichos niveles entre géneros (C: ♂100.41 ng/mL vs ♀50.54 ng/mL) y (Db: ♂26.77 ng/mL vs ♀39.7 ng/mL). Los niveles de LCN2 en Db...
