Helicobacter pylori (Hp) is a Gram negative bacillus that infects 80% of the world population. Hp infection activates both the innate and the adaptive immune response and is associated with different gastroduodenal diseases. However, only 30% of the infected population develops the some of the associated pathology. Toll-like receptors (TLRs)...
Introducción: En la fisiopatología de la esquizofrenia, se han sugerido factores genéticos asociados a la etiología de esta enfermedad y a la respuesta farmacológica, entre los que destacan genes de la vía de la respuesta inmune innata como TLR1, TLR2 y TLR6. Estos genes han mostrado alteraciones en su expresión...
Cardiovascular disease is the leading health problem worldwide and coronary artery disease (CAD) or ischemic heart disease are the second leading cause of death worldwide. Previous studies have found the involvement of uncoupling protein (UCP`s) in the development of risk factors for CAD, such as: dyslipidemia, obesity, diabetes, hypertension, and...
Epilepsy is the most common neurological disease and approximately 30% of patients who suffer from it do not respond to drug treatment, that is, they present drug-resistant epilepsy. Temporal lobe epilepsy (TLE) is the most frequent form of focal epilepsy in adults and the majority of patients with TLE hippocampal...