Synaptic vesicle protein 2A (SV2A) has become an attractive target of investigation due to its possible role in the pathophysiology of epilepsy. This protein is expressed ubiquitously in all nerve terminals independently of their neurotransmitter content. A decrease in SV2A levels has been reported in patients with refractory epilepsy and...
Epilepsy is the most common neurological disease and approximately 30% of patients who suffer from it do not respond to drug treatment, that is, they present drug-resistant epilepsy. Temporal lobe epilepsy (TLE) is the most frequent form of focal epilepsy in adults and the majority of patients with TLE hippocampal...