Some individuals show resistance to diseases and disorders even under adverse conditions (resilience), and others are more susceptible to them (vulnerability). Modifying litter size is a common method to study obesity and malnutrition, and its effects. Previous studies in our laboratory suggested that litter size negatively impacts sexual behavior, memory,...
Sleep loss produces blood-brain barrier (BBB) hyperpermeability by increasing endocytosis and promoting tight junction disassemble. Similar effects have been reported in mice with pericyte deficiency. In previous studies, we showed that pericytes seem to detach from the capillary wall in sleep-restricted animals. Thus, we aimed to evaluate the changes in...