Introduction. Is estimated that 9% of individuals between 14 and 19 years has made a suicide attempt (SA), of which 61% have major depressive disorder (MDD) and often aggressive. The SA involves genetic risk factors, among which serotonergic pathway genes (SLC6A4, 5HT1Dβ, TPH2 and MAOA) and dopaminergic pathway genes (DRD2...
Introducción: En la fisiopatología de la esquizofrenia, se han sugerido factores genéticos asociados a la etiología de esta enfermedad y a la respuesta farmacológica, entre los que destacan genes de la vía de la respuesta inmune innata como TLR1, TLR2 y TLR6. Estos genes han mostrado alteraciones en su expresión...
Background. Suicide behavior represents a worldwide public health problem. Estimates indicate that more than 800,000 people commit suicides per year and at least ten times more people present suicide attempt (SA). Family, twins and adoption studies have suggested that genetic factors are involved in suicidal behavior. Corticotrophin releasing hormone receptor...