Diabetes mellitus (DM) is a group of metabolic diseases characterized by chronic hyperglycemia, which is due to decreased secretion and/or activity of insulin, the hormone released by pancreatic β cells. During periods of hyperglycaemia, the hexoses react with proteins to form advanced glycation products (AGES), favoring the development of pathologic...
La diabetes mellitus tipo 2 (DT2) es un trastorno metabólico crónico caracterizado por hiperglucemia sostenida asociada con resistencia a la insulina (RI) y ausencia en la producción de insulina. La RI afecta a diferentes órganos, incluyendo al músculo esquelético y al hígado, lo cual contribuye a las alteraciones del metabolismo...
The overweight and the obesity are defined as abnormal or excessive fat accumulation that may impair the health. According to the World Health Organization, in 2005 approximately 1.6 billion of adults had overweight, whereas 400 million of adults were obese. Overweight and obesity are considered risk factors for developing type...
La diabetes mellitus (DM) comprende un grupo de enfermedades metabólicas que se caracteriza por hiperglucemia crónica, debido a disminución en la secreción y/o actividad de la insulina, hormona liberada por las células B del páncreas. Durante los períodos de hiperglucemia, las hexosas reaccionan con las proteínas, formando productos de glicación...
Cucurbita ficifolia Bouche (C. ficifolia) is a medicinal plant used in the treatment of diabetes mellitus (DM), a disease with an important epidemiological importance that lies in its high prevalence and mortality rates. There are experimental and clinical evidences about its hypoglycemic action. However, phytochemical and pharmacological studies are still...