Chagasí disease contributes significantly to cardiovascular morbidity and mortality in several Latin-American countries. Chronic human Chagas' disease ranges from an asymptomatic to a severe cardiac clinical form. The involvement of the host's immune response in the development and maintenance of chagasic pathology has been demonstrated by several groups. Chronic cardiac...
In the last decade it has been demonstrated that obesity entails adipose tissue immunophenotypic and systemic alterations, which are caused by the excessive and improper activation of the immune system. On that basis, a lowintensity chronic inflammatory process has been identified in the case of obesity as playing an important...
Sleep is an indispensable physiological activity, it is considered that the human being spends a third of his life sleeping, which indicates that the functions of sleep are of vital importance. Although the function of sleep is not fully described, several theories are considered, among them, it deters the regulation...
The cytokine IFN-g plays an important role in the adaptive immune response against Toxoplasma gondii, since it induces effector mechanisms against the tachyzoite, i.e. phagocytosis enhancement of macrophages, neutrophils and natural killer (NK) cells, as well as B cell production of antibodies of the IgG1 and IgG3 subclasses; the later...
