La diabetes mellitus (DM) es un síndrome provocado por la falla en la secreción y/o acción de la insulina que lleva a hiperglucemia y otros trastornos metabólicos. Actualmente, la DM representa uno de los problemas más importantes de la Medicina y es la tercera causa de muerte, después de las...
This work was designed to study an alternative treatment of diabetes mellitus by using a transplant of hybrid cells obtained by the electrofusion of pancreatic islet cells from a healthy donor with dermic cells from a diabetic recipient. The hybrid cells could keep the capacity of insulin production, its regulation,...
The mechanism by which hyperglycemia induces pancreatic β cell apoptosis is not completely understood. However, it is known that chronic states of hyperglycemia promote a state of oxidative stress that activates the p53 protein which participates in cell survival. The aim of this study was to find whether oxidative stress...
The type-2 Diabetes mellitus patients display a marked reduction in their life expectancy ranging from 5 to 10 years, as well as a strong tendency towards developing microvascular (neuropathy), macrovascular (myocardial infarction) complications and erectile dysfunction; that induces a reduction of the quality of life of these subjects and an...
Diabetes mellitus (DM) is a metabolic disease, and a chronic degenerative inflammatory condition characterized by hyperglycemia due to a deficiency in the secretion and/or insulin action that leads to irreversible development of vascular complications. The DM is classified into four categories being the most important type 1 diabetes mellitus (DM1),...